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| 12. |  | CORDEIRO, M. C. R.; SILVA, M. S.; MARTINS, N. F.; SÁ, M. F. G. de. Expressão de fatores de transcrição tipo WRKY no banco genoma funcional de café (Coffea sp.). In: SIMPÓSIO DE PESQUISA DOS CAFÉS DO BRASIL, 5., 2007, Águas de Lindóia, SP. Anais... Brasília, DF: Embrapa Café, 2007. 1 CD-ROM.| Biblioteca(s): Embrapa Cerrados. |
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Registro Completo
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Biblioteca(s): |
Embrapa Suínos e Aves. |
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Data corrente: |
05/10/2015 |
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Data da última atualização: |
26/01/2018 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Circulação/Nível: |
A - 1 |
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Autoria: |
PÉRTILLE, F.; ZANELLA, R.; FELÍCIO, A. M.; LEDUR, M. C.; PEIXOTO, J. de O.; COUTINHO, L. L. |
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Afiliação: |
FÁBIO PÉRTILLE, ESALQ; RICARDO ZANELLA, CNPq; ANDRESSA MARIA FELÍCIO, ESALQ; MONICA CORREA LEDUR, CNPSA; JANE DE OLIVEIRA PEIXOTO, CNPSA; LUIZ LEHMANN COUTINHO, ESALQ. |
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Título: |
Identification of polymorphisms associated with production traits on chicken (Gallus gallus) chromosome 4. |
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Ano de publicação: |
2015 |
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Fonte/Imprenta: |
Genetics and Molecular Research, v. 14, n. 3, p. 10717-10728, 2015. |
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DOI: |
http://dx.doi.org/10.4238/2015.September.9.11 |
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Idioma: |
Inglês |
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Conteúdo: |
Genetic selection for production traits has resulted in a rapid improvement in animal performance and development. Previous studies have mapped quantitative trait loci for body weight at 35 and 41 days, and drum and thigh yield, onto chicken chromosome 4. We investigated this region for single nucleotide polymorphisms and their associations with important economic traits. Three positional candidate genes were studied: KLF3 (Krüeppel-like factor 3), SLIT2 (Slit homolog 2), and PPARGC1A (peroxisome proliferator-activated receptor gamma, coactivator 1 alpha). Fragment sequencing of these genes was conducted in 11 F1 animals, and one polymorphism in each gene was selected and genotyped in an F2 population (N = 276) and a paternal broiler line TT (N = 840). Associations were identified with growth, carcass, and fat traits in the F2 and the paternal line (P < 0.05). Using single markers in both the F2 and the TT line, KLF3 was associated with weight gain (P < 0.05), PPPARGC1A was associated with liver and wing-parts weights and yields (P < 0.05), and SLIT2 was associated with back yield (P < 0.05) and fat traits (P < 0.05). Using multiple markers, KLF3 lost its significance in both populations, and SLIT2 was associated with feed conversion only in the TT population (P < 0.05). The QTLs mapped in the F2 population could be partly explained by PPARGC1A and SLIT2, which were associated with body weight at 35 and 41 days, respectively, and with drum and thigh yield in the same population. The results of this study indicate the importance of these genes for production traits. MenosGenetic selection for production traits has resulted in a rapid improvement in animal performance and development. Previous studies have mapped quantitative trait loci for body weight at 35 and 41 days, and drum and thigh yield, onto chicken chromosome 4. We investigated this region for single nucleotide polymorphisms and their associations with important economic traits. Three positional candidate genes were studied: KLF3 (Krüeppel-like factor 3), SLIT2 (Slit homolog 2), and PPARGC1A (peroxisome proliferator-activated receptor gamma, coactivator 1 alpha). Fragment sequencing of these genes was conducted in 11 F1 animals, and one polymorphism in each gene was selected and genotyped in an F2 population (N = 276) and a paternal broiler line TT (N = 840). Associations were identified with growth, carcass, and fat traits in the F2 and the paternal line (P < 0.05). Using single markers in both the F2 and the TT line, KLF3 was associated with weight gain (P < 0.05), PPPARGC1A was associated with liver and wing-parts weights and yields (P < 0.05), and SLIT2 was associated with back yield (P < 0.05) and fat traits (P < 0.05). Using multiple markers, KLF3 lost its significance in both populations, and SLIT2 was associated with feed conversion only in the TT population (P < 0.05). The QTLs mapped in the F2 population could be partly explained by PPARGC1A and SLIT2, which were associated with body weight at 35 and 41 days, respectively, and with drum and thigh yield in the same populat... Mostrar Tudo |
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Palavras-Chave: |
Broiler. |
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Thesagro: |
Ave doméstica; Genetica animal; Genoma; Polimorfismo genético. |
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Thesaurus NAL: |
Gallus gallus; Genetic polymorphism; Polymorphism; Quantitative trait loci. |
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Categoria do assunto: |
-- |
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URL: |
https://ainfo.cnptia.embrapa.br/digital/bitstream/item/130778/1/final7994.pdf
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Marc: |
LEADER 02531naa a2200301 a 4500
001 2025835
005 2018-01-26
008 2015 bl uuuu u00u1 u #d
024 7 $ahttp://dx.doi.org/10.4238/2015.September.9.11$2DOI
100 1 $aPÉRTILLE, F.
245 $aIdentification of polymorphisms associated with production traits on chicken (Gallus gallus) chromosome 4.$h[electronic resource]
260 $c2015
520 $aGenetic selection for production traits has resulted in a rapid improvement in animal performance and development. Previous studies have mapped quantitative trait loci for body weight at 35 and 41 days, and drum and thigh yield, onto chicken chromosome 4. We investigated this region for single nucleotide polymorphisms and their associations with important economic traits. Three positional candidate genes were studied: KLF3 (Krüeppel-like factor 3), SLIT2 (Slit homolog 2), and PPARGC1A (peroxisome proliferator-activated receptor gamma, coactivator 1 alpha). Fragment sequencing of these genes was conducted in 11 F1 animals, and one polymorphism in each gene was selected and genotyped in an F2 population (N = 276) and a paternal broiler line TT (N = 840). Associations were identified with growth, carcass, and fat traits in the F2 and the paternal line (P < 0.05). Using single markers in both the F2 and the TT line, KLF3 was associated with weight gain (P < 0.05), PPPARGC1A was associated with liver and wing-parts weights and yields (P < 0.05), and SLIT2 was associated with back yield (P < 0.05) and fat traits (P < 0.05). Using multiple markers, KLF3 lost its significance in both populations, and SLIT2 was associated with feed conversion only in the TT population (P < 0.05). The QTLs mapped in the F2 population could be partly explained by PPARGC1A and SLIT2, which were associated with body weight at 35 and 41 days, respectively, and with drum and thigh yield in the same population. The results of this study indicate the importance of these genes for production traits.
650 $aGallus gallus
650 $aGenetic polymorphism
650 $aPolymorphism
650 $aQuantitative trait loci
650 $aAve doméstica
650 $aGenetica animal
650 $aGenoma
650 $aPolimorfismo genético
653 $aBroiler
700 1 $aZANELLA, R.
700 1 $aFELÍCIO, A. M.
700 1 $aLEDUR, M. C.
700 1 $aPEIXOTO, J. de O.
700 1 $aCOUTINHO, L. L.
773 $tGenetics and Molecular Research$gv. 14, n. 3, p. 10717-10728, 2015.
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Embrapa Suínos e Aves (CNPSA) |
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